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X-WR-CALNAME:Regensburg Center for Ultrafast Nanoscopy
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X-WR-CALDESC:Events for Regensburg Center for Ultrafast Nanoscopy
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DTSTART;TZID=Europe/Berlin:20260611T140000
DTEND;TZID=Europe/Berlin:20260611T160000
DTSTAMP:20260607T034746
CREATED:20260519T125954Z
LAST-MODIFIED:20260603T083642Z
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SUMMARY:RTG Colloquium: Gabriele Kaminski Schierle & Clemens Kaminski
DESCRIPTION:Biological imaging at the nanoscale\n\n\n\nClemens F. Kaminski\, University of Cambridge \n\n\n\nThe advent of optical super‑resolution imaging together with the ability to label specific cellular components with fluorescent markers has ushered in a revolution in our mechanistic understanding of biological processes. In this presentation\, I will provide an overview of current methods used to obtain nanoscale insights into the molecular machinery that supports life at the subcellular level. I will present approaches for tracking protein interactions\, using single‑molecule localisation microscopy as well as indirect techniques such as fluorescence lifetime imaging microscopy. I will then discuss methods based on structured illumination microscopy\, which enable dynamic interrogation of cellular machinery including lysosomes and the endoplasmic reticulum. Finally\, I will offer an outlook on emerging trends and how machine learning is transforming our field. \n\n\n\nCoffee break & discussion \n\n\n\nBeyond Alzheimer’s: conserved lysosomal dyshomeostasis as a driver of synaptic dysfunction across neurodegenerative proteopathies\n\n\n\nGabriele S. Kaminski Schierle\, University of Cambridge \n\n\n\nWhile scientists know that in Alzheimer’s disease\, lysosomes (the cell’s “trash cans”) clump together and lose their acidity\, they didn’t know if this happens in all neurodegenerative diseases.This study found that this “trash can” breakdown actually happens across many diseases\, including ALS\, Parkinson’s\, and Frontotemporal Dementia. Instead of being spread out normally to clean the whole cell\, the lysosomes clump tightly around the cell’s centre.By tracking cell electricity and layout\, the researchers discovered that this clumping severely damages brain signalling. Because the lysosomes are stuck in the centre\, they can’t reach the distant outer branches of the brain cells to clear out old\, broken proteins. This causes waste to build up and shorts out communication between neurons.Ultimately\, this suggests that fixing where lysosomes sit and restoring their acidity could act as a single\, powerful treatment for multiple brain diseases. \n\n\n\nVenue: RUN Auditorium
URL:https://run-regensburg.de/event/rtg-colloquium-gabriele-kaminski-schierle-clemens-kaminski/
CATEGORIES:RTG Colloquium
ATTACH;FMTTYPE=image/png:https://run-regensburg.de/wp-content/uploads/2026/05/Kaminskis2.png
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DTSTART;TZID=Europe/Berlin:20260619T140000
DTEND;TZID=Europe/Berlin:20260619T150000
DTSTAMP:20260607T034747
CREATED:20260513T135656Z
LAST-MODIFIED:20260603T082149Z
UID:4137-1781877600-1781881200@run-regensburg.de
SUMMARY:RTG Colloquium: Alice Kunin
DESCRIPTION:High-performance time-resolved photoemission experiments of quantum materials\n\n\n\nPrinceton University \n\n\n\nI will discuss our work coupling MHz\, kW light sources with momentum microscopy to enable efficient time- and angle-resolved photoemission (tr-ARPES) studies. I will first examine the dynamics of intra- and interlayer excitons in twisted van der Waals heterobilayers. I will then discuss our current work on a new spectrometer to probe ultrafast surface photochemistry in situ with the extension of tr-ARPES beyond ultrahigh vacuum towards more realistic chemical environments. \n\n\n\nVenue: RUN Auditorium
URL:https://run-regensburg.de/event/rtg-colloquium-alice-kunin/
CATEGORIES:RTG Colloquium
ATTACH;FMTTYPE=image/png:https://run-regensburg.de/wp-content/uploads/2026/05/people_alice-768x768-1.png
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DTSTART;TZID=Europe/Berlin:20260703T140000
DTEND;TZID=Europe/Berlin:20260703T150000
DTSTAMP:20260607T034747
CREATED:20260513T140017Z
LAST-MODIFIED:20260513T140017Z
UID:4142-1783087200-1783090800@run-regensburg.de
SUMMARY:RTG Colloquium: Bruno Schuler
DESCRIPTION:Empa\, Switzerland \n\n\n\nVenue: RUN Auditorium
URL:https://run-regensburg.de/event/rtg-colloquium-bruno-schuler/
CATEGORIES:RTG Colloquium
ATTACH;FMTTYPE=image/jpeg:https://run-regensburg.de/wp-content/uploads/2026/05/citations.jpg
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